Compulsions, Aggression, and Self-Mutilation: A Hypothalamic Disorder?
نویسنده
چکیده
Twelve patients characterized by aggressive behavior, obsessive-compulsive symptoms, selfmutilation, sexual disorders, insomnia, and disturbances in the family constellation are described. Secondary findings in some patients included high pain threshold, abnormal EEC, and altered glucose-tolerance curves. Nine had a past history of anorexia nervosa and four patients of psychosis. Out of eight treated cases, chlorimipramine* (CLI), a potent serotonin re-uptake blocker, relieved symptoms in six patients and worsened them in two cases with a history of psychosis. A hypothalamic dysfunction related to a serotonergic imbalance is offered as a hypothesis of work.
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